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Which nerve block wins for kidney surgery pain?

NCT ID NCT07781930

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 24, 2026 · Last updated Aug 25, 2026 · Updated 1 time

Summary

This trial compares two ultrasound-guided nerve blocks—TAP and ESPB—to see which provides better pain relief after laparoscopic kidney surgery. Sixty adults (18-40 years) will be randomly assigned to receive one of the blocks during surgery. Researchers will measure pain scores and total opioid use over 24 hours, along with time to first painkiller request and patient satisfaction. The goal is to identify a more effective approach to manage post-surgical pain and reduce opioid consumption.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ultrasound-guided nerve block (TAP or ESPB) using bupivacaine
What this could lead to
If one block proves better, it could lead to improved pain control and less opioid use after kidney surgery, enhancing recovery.
What could go wrong
This is a small, early-stage trial, so results may not apply to all patients. Nerve blocks carry risks like infection, bleeding, or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Age from 18 to 40 years old. * Both sexes. * American Society of Anesthesiology (ASA) physical status I, II. * Scheduled for laparoscopic renal surgeries under general anesthesia Exclusion criteria: * Parent's refusal. * Coagulation disorders. * History of allergy to local anesthetics. * Infection or redness at the injection site. * History of renal and/or hepatic insufficiency. * Preexisting cardiac dysfunction.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain, acute

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Kasr Al-Ainy hospital

    RECRUITING

    Cairo, 11562, Egypt

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