Can a pill combo spare men from a catheter after a urinary emergency?

NCT ID NCT07654413

Recruiting now Symptom relief Sponsor: Beni-Suef University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding tadalafil (a daily pill for erection problems and enlarged prostate) to standard tamsulosin helps men aged 50+ who suddenly can't urinate due to an enlarged prostate. After a catheter is placed, participants take either tamsulosin plus tadalafil or tamsulosin plus a placebo for up to 14 days. The main goal is to see if more men can urinate on their own and stay catheter-free by day 14.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tamsulosin and tadalafil
What this could lead to: If it works, this could offer a better way to help men with an enlarged prostate avoid a catheter after a sudden inability to urinate.
What could go wrong: This is a phase 4 trial, so the drugs are already approved, but the combination may not improve success rates and could cause side effects like headache or dizziness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE URINARY RETENTION BENIGN PROSTATIC HYPERPLASIA BENIGN PROSTATIC OBSTRUCTION

Contacts and locations

Locations

Department of Urology- Beni-Suef University Hospitals
RECRUITING

Banī Suwayf, Beni Suweif Governorate, 02456, Egypt

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