Tampon test could spot hidden cancers early

NCT ID NCT03538665

Recruiting now Diagnosis Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 30, 2026 · Updated 4 times

Summary

This study explores whether a tampon can collect DNA samples from the vagina to detect endometrial and ovarian cancer early. Researchers will compare tampon samples with tissue and blood from 1,500 women undergoing surgery. The goal is to develop a simple, non-invasive screening tool that could improve early detection and reduce racial disparities in cancer outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple, at-home tampon-based test for early detection of endometrial and ovarian cancer, potentially saving lives.
What could go wrong: This is an early-stage study focused on feasibility and sample collection, not yet proving the test works for cancer detection. Results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atypical endometrial hyperplasia endometrial cancer endometrium neoplasm ovarian cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COMPLEX ATYPICAL ENDOMETRIAL HYPERPLASIA ENDOMETRIAL CANCER ENDOMETRIAL CANCER PRECURSORS OVARIAN CANCER

Contacts and locations

Locations

University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35233, United States

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