New combo therapy may help liver cancer patients bridge to transplant

NCT ID NCT01918683

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot trial is testing whether adding stereotactic body radiation therapy (SBRT) to the standard transarterial chemoembolization (TACE) can better control liver cancer in patients waiting for a liver transplant. About 40 patients will be enrolled to see if the combination improves progression-free survival until transplant. The goal is to keep the cancer from growing so patients can successfully receive a new liver.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transarterial chemoembolization (TACE) and stereotactic body radiation therapy (SBRT)

What this could lead to

If successful, this combination could help more liver cancer patients stay healthy enough to receive a transplant and improve their chances of a good outcome after surgery.

What could go wrong

This is a small, early pilot study with only 40 participants, so results may not apply to everyone. The combination of treatments may also cause side effects like liver damage or fatigue.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Abramson Cancer Center of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Loyola University Medical Center

    Maywood, Illinois, 60153, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States