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Massive study aims to settle debate on colon cancer surgery extent

NCT ID NCT02938481

Completed Knowledge-focused Sponsor: Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study followed over 3,600 people with stage I to III colon cancer who had surgery. The goal was to learn how far cancer spreads to lymph nodes and how much bowel and tissue should be removed for the best outcome. The results could help guide surgeons in the future, but this was an observational study, not a test of a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help surgeons know exactly how much bowel and how many lymph nodes to remove during colon cancer surgery, improving outcomes.

What could go wrong

This is an observational study, not a treatment trial, so it does not test a new drug or therapy. The results may not apply to all patients or change practice directly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colon adenocarcinoma colon carcinoma colonic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLON CANCER

Contacts and locations

Locations

  • Aichi Cancer Centre Hospital

    Nagoya, Aichi-ken, 464-8681, Japan

  • China Medical University Hospital

    Taichung, 40447, Taiwan

  • Fujita Health University

    Toyoake, Aichi-ken, 470-1192, Japan

  • I.M. Sechenov First Moscow State Medical University

    Moscow, Russia

  • Kanagawa Cancer Centre Hospital

    Yokohama, Kanagawa, 241-8515, Japan

  • Keiyukai Sapporo Hospital

    Sapporo, Hokkaido, 003-0027, Japan

  • Klaipeda University hospital

    Klaipėda, Lietuva, Lithuania

  • Kurume University School of Medicine

    Kurume, Hukuoka-prefecture, 830-0011, Japan

  • Kyorin University School of Medicine

    Mitaka, Tokyo, 181-8611, Japan

  • Mie University Graduate School of Medicine

    Tsu, Mie-ken, 514-8507, Japan

  • National Cancer Centre Central Hospital

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Cancer Institute, Lithuania

    Vilnius, Lithuania

  • National Canser Centre Hospital East

    Chiba, Chiba, 277-8577, Japan

  • National Defense Medical College

    Tokorozawa, Saitama, 359-8513, Japan

  • National Taiwan University Hospital

    Taipei, Taiwan

  • Niigata Cancer Center Hospital

    Niigata, Niigata, Japan

  • Osaka International Cancer Institute

    Osaka, Osaka, 537-8511, Japan

  • Saisei-kai Yokohama-shi Nanbu Hospital

    Yokohama, Kanagawa, 234-0054, Japan

  • Saitama Cancer Center

    Kitaadachi-gun, Saitama, 362-0806, Japan

  • Shiga University of Medical Science

    Ōtsu, Shiga, Japan

  • Shizuoka Cancer Centre Hospital

    Sunto-gun, Shizuoka, 411-8777, Japan

  • Takano Hospital

    Kumamoto, Kumamoto, 862-0924, Japan

  • Teikyo University Chiba Medical Center

    Ichihara-shi, Chiba, Japan

  • Teikyo University School of Medicine

    Itabashi-ku, Tokyo, 173-8605, Japan

  • Tochigi Cancer Center

    Utsunomiya, Tochigi, Japan

  • Tokyo Medical and Dental University

    Bunkyo-ku, Tokyo, 113-8519, Japan

  • Tokyo Metropolitan Cancer and Infectious Disease Centre Komagome Hospital

    Bunkyo-ku, Tokyo, 113-8677, Japan

  • Tokyo Women's Medical University

    Shinjuku-ku, Tokyo, 162-8666, Japan

  • University Hospital Erlangen

    Erlangen, Bavaria, 91054, Germany

  • University of Leeds

    Leeds, West Yorkshire, LS2 9JT, United Kingdom

  • University of Ulsan College of Medicine and Asan Medical Center

    Songpa-Gu, Seoul, South Korea

  • Wakayama Medical University

    Wakayama, Wakayama, Japan

  • Yamagata Prefectural Central Hospital

    Yamagata, Yamagata, 990-2292, Japan

  • Yokohama City University Medical Center

    Yokohama, Kanagawa, 232-0024, Japan

  • Yokohama-city University

    Yokohama, Kanagawa, 236-0004, Japan

  • Yonsei University

    Seodaemun-gu, Seoul, 03722, South Korea