Engineered T-Cells take on blood cancers in early trial
NCT ID NCT00709033
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tested a new type of cell therapy for people with advanced B-cell non-Hodgkin lymphoma or chronic lymphocytic leukemia (CLL) that had returned or not responded to standard treatments. Researchers took patients' own immune cells (T-cells) and added a special receptor (CD19-CD28) or trained them to recognize the Epstein-Barr virus (EBV) to help them attack cancer cells more effectively. The main goals were to find a safe dose and see how long the modified cells lasted in the body.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Houston Methodist Hospital
Houston, Texas, 77030, United States
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Texas Children's Hospital
Houston, Texas, 77030, United States
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