Genetic test could tailor blood thinners after stents, reducing bleeding risk

NCT ID NCT06588595

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a genetic score (ABCD-GENE) can help doctors choose the right blood thinner for patients after a heart stent. Currently, patients take two blood thinners for months. The score would guide whether to switch to a milder drug or drop one of the two. The trial involves 90 adults who have had a stent and are on standard dual therapy. Researchers will measure how well the blood is thinned, aiming to find a safer, personalized approach.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Prasugrel, Ticagrelor, Clopidogrel, Aspirin

What this could lead to

If successful, this could show that using a genetic test to choose blood thinners after a heart stent is safer and just as effective as the standard one-size-fits-all approach.

What could go wrong

This is a small, early-phase study (90 people) that only measures blood reactivity, not actual heart attacks or strokes. The genetic score may not work as well in real-world, diverse populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Florida

    RECRUITING

    Jacksonville, Florida, 32209, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••