Brain cancer trial aims to delay tumor return by zapping stem cells

NCT ID NCT02177578

First seen Jan 11, 2026 · Last updated May 16, 2026 · Updated 19 times

Summary

This study tests whether giving a higher radiation dose to a specific brain area (the subventricular zone) alongside standard radiation and chemotherapy can delay glioblastoma from coming back. About 60 adults with newly diagnosed glioblastoma will be randomly assigned to receive either the modified radiation or standard treatment. The goal is to see if targeting this stem-cell-rich region improves tumor control.

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Contacts and locations

Locations

  • Sibley Memorial Hospital

    Washington D.C., District of Columbia, United States

  • Suburban Hospital

    Bethesda, Maryland, United States

  • The SKCCC at Johns Hopkins

    Baltimore, Maryland, 21287, United States

Conditions

Explore the condition pages connected to this study.