Brain cancer trial aims to outsmart recurrence by zapping stem cells

NCT ID NCT02177578

Ongoing Disease control Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study tests whether giving a higher radiation dose to a brain area called the subventricular zone (where stem cells live) can delay glioblastoma from coming back. About 60 adults with newly diagnosed glioblastoma will receive standard radiation and chemo, but half will get extra radiation to that stem cell region. The goal is to see if this approach keeps the tumor under control longer than standard treatment alone.

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Conditions

The condition(s) this trial relates to.

glioblastoma glioma susceptibility 1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOBLASTOMA MULTIFORME

Contacts and locations

Locations

Sibley Memorial Hospital

Washington D.C., District of Columbia, United States
Suburban Hospital

Bethesda, Maryland, United States
The SKCCC at Johns Hopkins

Baltimore, Maryland, 21287, United States

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