Heated chemo during surgery may fight chest tumor spread
NCT ID NCT07383142
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares surgery alone to surgery plus heated chemotherapy (HITOC) for people with thymic tumors that have spread to the lining of the chest. About 202 participants will be randomly assigned to one of the two groups. The goal is to see if adding HITOC helps keep the cancer from coming back longer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- doxorubicin and cisplatin (heated chemotherapy)
- What this could lead to
- If it works, this could offer a better way to control thymic tumors that have spread to the chest lining, potentially delaying recurrence.
- What could go wrong
- This is a Phase 3 trial, but it hasn't started recruiting yet. The heated chemotherapy adds risks like infection or organ damage, and it may not improve survival over surgery alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Shanghai Zhongshan Hospital
Shanghai, 200032, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Shorter radiation after thymic tumor surgery may cut side effects
- Fewer radiation sessions may be just as effective for thymic tumors after surgery
- Heated chemo after surgery shows promise for rare chest cancer spread
- New hope for rare thymus cancers: PT-112 trial launches
- Experimental drug targets rare thymus cancers after chemotherapy fails
- Scientists dive deep into thymic tumors to unlock new clues