Heated chemo during surgery may fight chest tumor spread

NCT ID NCT07383142

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares surgery alone to surgery plus heated chemotherapy (HITOC) for people with thymic tumors that have spread to the lining of the chest. About 202 participants will be randomly assigned to one of the two groups. The goal is to see if adding HITOC helps keep the cancer from coming back longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
doxorubicin and cisplatin (heated chemotherapy)
What this could lead to
If it works, this could offer a better way to control thymic tumors that have spread to the chest lining, potentially delaying recurrence.
What could go wrong
This is a Phase 3 trial, but it hasn't started recruiting yet. The heated chemotherapy adds risks like infection or organ damage, and it may not improve survival over surgery alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai Zhongshan Hospital

    Shanghai, 200032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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