Can prostate removal boost survival in advanced cancer?

NCT ID NCT03456843

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 32 times

Summary

This study tests whether surgically removing the prostate, along with hormone therapy and possibly chemotherapy, helps men with prostate cancer that has spread to other parts of the body. About 190 men with newly diagnosed metastatic prostate cancer will be randomly assigned to receive either standard therapy alone or standard therapy plus surgery. The goal is to see if adding surgery delays cancer progression and improves quality of life.

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Contacts and locations

Locations

  • Akita University

    Akita, Japan

  • Chinese University of Hong Kong

    Hong Kong, China

  • City of Hope

    Duarte, California, 91010, United States

  • Epworth Healthcare

    East Melbourne, Australia, 9084, Australia

  • Juntendo University

    Tokyo, Japan

  • Kindai University

    Ōsaka-sayama, Osaka, 589-8511, Japan

  • National Cancer Center

    Goyang-si, South Korea

  • National Taiwan University Hospital

    Taipei, Taiwan

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • Samsung Medical Center

    Seoul, South Korea

  • Seoul National University Bundang Hospital

    Gyeonggi-do, South Korea

  • Swedish Medical Services

    Seattle, Washington, 98104, United States

  • University of California, Irvine

    Irvine, California, 92697, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Southern California

    Los Angeles, California, 90033, United States

  • Yale University

    New Haven, Connecticut, 06519, United States

Conditions

Explore the condition pages connected to this study.