Can surgery boost survival in metastatic prostate cancer?

NCT ID NCT03456843

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether surgically removing the prostate, along with hormone therapy and possibly chemotherapy, can help men whose prostate cancer has already spread. About 190 men with newly diagnosed stage IV prostate cancer will be randomly assigned to get either standard drug therapy alone or standard drug therapy plus surgery. The goal is to see if adding surgery delays cancer progression and improves quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metastatic prostate carcinoma prostate adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Akita University

    Akita, Japan

  • Chinese University of Hong Kong

    Hong Kong, China

  • City of Hope

    Duarte, California, 91010, United States

  • Epworth Healthcare

    East Melbourne, Australia, 9084, Australia

  • Juntendo University

    Tokyo, Japan

  • Kindai University

    Ōsaka-sayama, Osaka, 589-8511, Japan

  • National Cancer Center

    Goyang-si, South Korea

  • National Taiwan University Hospital

    Taipei, Taiwan

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • Samsung Medical Center

    Seoul, South Korea

  • Seoul National University Bundang Hospital

    Gyeonggi-do, South Korea

  • Swedish Medical Services

    Seattle, Washington, 98104, United States

  • University of California, Irvine

    Irvine, California, 92697, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Southern California

    Los Angeles, California, 90033, United States

  • Yale University

    New Haven, Connecticut, 06519, United States