Can surgery boost survival in metastatic prostate cancer?
NCT ID NCT03456843
First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This study looks at whether surgically removing the prostate, along with hormone therapy and possibly chemotherapy, can help men whose prostate cancer has already spread. About 190 men with newly diagnosed stage IV prostate cancer will be randomly assigned to get either standard drug therapy alone or standard drug therapy plus surgery. The goal is to see if adding surgery delays cancer progression and improves quality of life.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Akita University
Akita, Japan
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Chinese University of Hong Kong
Hong Kong, China
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City of Hope
Duarte, California, 91010, United States
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Epworth Healthcare
East Melbourne, Australia, 9084, Australia
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Juntendo University
Tokyo, Japan
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Kindai University
Ōsaka-sayama, Osaka, 589-8511, Japan
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National Cancer Center
Goyang-si, South Korea
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National Taiwan University Hospital
Taipei, Taiwan
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903, United States
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Samsung Medical Center
Seoul, South Korea
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Seoul National University Bundang Hospital
Gyeonggi-do, South Korea
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Swedish Medical Services
Seattle, Washington, 98104, United States
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University of California, Irvine
Irvine, California, 92697, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Southern California
Los Angeles, California, 90033, United States
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Yale University
New Haven, Connecticut, 06519, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Chemo combo vs. radioactive drug: which tames aggressive prostate cancer?
- Can a blood filtering technique reveal more about prostate cancer spread?
- Can a vaccine plus immune booster tackle resistant prostate cancer?
- Can a smart drug deliver a toxic payload to prostate cancer cells?
- Can a blast of testosterone shrink hard-to-treat prostate cancer?
- A PET scan and a blood test may predict which men with advanced prostate cancer will benefit from targeted therapy