New method aims to help premature babies breathe easier without a breathing tube

NCT ID NCT07176117

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving surfactant (a natural substance that helps lungs stay open) through a small airway device placed above the vocal cords, along with standard breathing support (CPAP), is better than CPAP alone for late preterm and early term infants with respiratory distress. About 422 newborns will be enrolled. The goal is to see if this less invasive approach reduces complications and hospital stays.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

surfactant

What this could lead to

If successful, this could provide a safer, less invasive way to treat breathing problems in newborns, potentially reducing complications and hospital stays.

What could go wrong

This is a single-center study, and results may not apply to all hospitals. The procedure still carries risks like any airway device, and the benefit over standard CPAP alone is not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pulmonary Atelectasis respiratory distress syndrome in premature infants

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sharp Chula Vista Medical Center

    Chula Vista, California, 91911, United States

  • Sharp Grossmont Hospital

    La Mesa, California, 91942, United States

  • Sharp Mary Birch Hospital for Women & Newborns

    San Diego, California, 92123, United States