New device offers hope for heart failure patients not helped by standard drugs

NCT ID NCT03836079

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 28 times

Summary

This study tested a device called preCARDIA that temporarily blocks a large vein in the chest to help patients with severe acute heart failure who are not getting better with standard water pills. The study included 60 adults with advanced heart failure. The main goal was to see if the device is safe and works well over 90 days.

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Contacts and locations

Locations

  • Allegheny General Hospital

    Pittsburgh, Pennsylvania, 15212, United States

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Baylor, Scott & White Medical Center - Temple

    Temple, Texas, 76508, United States

  • CentraCare Heart & Vascular Center

    Saint Cloud, Minnesota, 56303, United States

  • Colorado Heart & Vascular

    Lakewood, Colorado, 80226, United States

  • Houston Methodist

    Houston, Texas, 77030, United States

  • Inova Health System

    Falls Church, Virginia, 22042, United States

  • Kansas University Medical Center

    Kansas City, Kansas, 66160, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Medstar Washington Hospital Center

    Washington D.C., District of Columbia, 20010, United States

  • Minneapolis Heart Institute Foundation

    Minneapolis, Minnesota, 55407, United States

  • Northwestern

    Chicago, Illinois, 60611, United States

  • OhioHealth

    Columbus, Ohio, 43214, United States

  • Providence Health & Services

    Portland, Oregon, 97225, United States

  • Tampa General Hospital

    Tampa, Florida, 33606, United States

  • Tufts Medical Center

    Boston, Massachusetts, 02111, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.