Stent vs. scalpel: can a tiny tube replace surgery for leg artery disease?

NCT ID NCT04349657

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a new stent (Supera) to standard surgery for treating blockages in the leg's main artery. About 286 people with moderate to severe leg pain or sores will be randomly assigned to get either the stent or surgery. Researchers will check if the stent keeps the artery open as well as surgery and if it causes fewer complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Supera Peripheral Stent System

What this could lead to

If successful, this could offer a less invasive alternative to surgery for treating blocked leg arteries, potentially reducing recovery time and complications.

What could go wrong

This is a mid-stage trial with 286 participants. The stent may not work as well as surgery, or could cause complications like re-blockage or bleeding. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • A.Z. Jan Portaels

    Vilvoorde, 1800, Belgium

  • A.Z. Sint-Blasius

    Dendermonde, 9200, Belgium

  • AZ Sint-Maarten

    Mechelen, 2800, Belgium

  • Az Groeninge

    Kortrijk, 8500, Belgium

  • Bonifraterskie Centrum Medyczne

    Krakow, 31-061, Poland

  • Dijklander hospital

    Hoorn, North Holland, 1624, Netherlands

  • Imelda Hospital

    Bonheiden, 2820, Belgium

  • Karol Marcinkowski Medical University

    Poznan, 61-848, Poland

  • Maastricht UMC+

    Maastricht, Limburg, 6229, Netherlands

  • Noordwest ziekenhuisgroep

    Alkmaar, 1815, Netherlands

  • O.L.V. Hospital

    Aalst, 9300, Belgium

  • St Antonius Hospital

    Utrecht, Utrecht, 3543, Netherlands

  • Z.O.L.

    Genk, 3600, Belgium