New radiation approach aims to safely treat Hard-to-Reach lung tumors
NCT ID NCT03306680
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This phase 1 trial tests a precise, high-dose radiation technique called SBRT for patients with non-small cell lung cancer whose tumors are located in the ultra-central part of the chest, near the windpipe and major blood vessels. The study enrolls 30 participants to find the highest safe dose that keeps the risk of serious side effects under 30% within two years. Researchers will also track cancer progression, survival, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy (SBRT)
What this could lead to
If successful, this could establish a safer radiation dose for hard-to-treat lung tumors located near the center of the chest.
What could go wrong
This is an early-phase trial with only 30 participants, so results may not apply broadly. The main risk is serious side effects from radiation hitting nearby vital structures.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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BC Cancer -Vancouver Island
Vancouver, British Columbia, V8R 6V5, Canada
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Centre Hospitalier de l'Universite de Montreal (CHUM)
Montreal, Quebec, H2X 0A9, Canada
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London Regional Cancer Program
London, Ontario, N6A 4L6, Canada
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McGill University Health Centre-Cedars Cancer Centre
Montreal, Quebec, H4A 3J1, Canada
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Princess Margaret Cancer Centre
Toronto, Ontario, M5G 1X6, Canada
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Saskatoon Cancer Centre
Saskatoon, Saskatchewan, S7S 0B1, Canada
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Sunnybrook Odette Cancer Centre
Toronto, Ontario, M4N 3M5, Canada