Soda science: new biomarkers could track your sugar intake without Self-Reporting

NCT ID NCT04799301

Recruiting now Knowledge-focused Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 17, 2026 · Updated 5 times

Summary

This study aims to find better ways to measure what people eat, specifically sugar from soda. Researchers will have 60 healthy adults live in a clinic for 13 weeks, eating controlled diets with different amounts of soda. They will then test if stable isotopes in blood, hair, and other samples can accurately reflect how much sugar was consumed. The goal is to develop objective biomarkers that could replace unreliable self-reported diet data in future research.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: diet with controlled soda intake
What this could lead to: If successful, this could provide a more accurate way to measure sugar intake in research, helping scientists better understand diet's role in chronic diseases.
What could go wrong: This is an early-phase study with only 60 healthy volunteers, so results may not apply to the general population. The biomarkers may not prove reliable enough for widespread use.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIET THERAPY HEALTHY VOLUNTEERS

Contacts and locations

Locations

NIDDK, Phoenix
RECRUITING

Phoenix, Arizona, 85014, United States

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