Can you safely stop opioid addiction meds? small study explores the exit strategy
NCT ID NCT05878210
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at 12 people with opioid use disorder who had been stable on SUBLOCADE injections for at least 9 months. Researchers wanted to see if they could successfully stop the medication without relapsing or restarting long-term treatment. The goal was to understand the withdrawal experience and how well people manage after stopping.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SUBLOCADE (buprenorphine extended-release injection)
What this could lead to
If successful, this could help doctors and patients understand the best way to safely stop long-term opioid addiction medication without relapse.
What could go wrong
This is a very small, completed observational study with only 12 participants, so results may not apply to everyone. It does not test a new treatment.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Comprehensive Addiction Medicine
Portland, Maine, 04102, United States
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Savera Medical Centre
Edmonton, Alberta, T6E6T9, Canada