Can you safely stop opioid addiction meds? small study explores the exit strategy

NCT ID NCT05878210

Completed Knowledge-focused Sponsor: Indivior Inc. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 12 people with opioid use disorder who had been stable on SUBLOCADE injections for at least 9 months. Researchers wanted to see if they could successfully stop the medication without relapsing or restarting long-term treatment. The goal was to understand the withdrawal experience and how well people manage after stopping.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SUBLOCADE (buprenorphine extended-release injection)
What this could lead to: If successful, this could help doctors and patients understand the best way to safely stop long-term opioid addiction medication without relapse.
What could go wrong: This is a very small, completed observational study with only 12 participants, so results may not apply to everyone. It does not test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID-USE DISORDER

Contacts and locations

Locations

Comprehensive Addiction Medicine

Portland, Maine, 04102, United States
Savera Medical Centre

Edmonton, Alberta, T6E6T9, Canada

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