New targeted cancer drug enters human trials for advanced tumors

NCT ID NCT05768139

Recruiting now Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

Summary

This early-stage study is testing a new targeted cancer drug called STX-478, both alone and in combination with other approved cancer therapies. It aims to find a safe dose and see if it can help control advanced solid tumors, particularly breast cancer, that have a specific genetic mutation. The study will enroll about 720 adults whose cancer has progressed despite other treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

Azienda Ospedaliera Nazionale Santi Antonio e Biagio e Cesare Arrigo
NOT_YET_RECRUITING

Alessandria, 15100, Italy

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Azienda Ospedaliero Universitaria Pisana - Stabilimento Santa Chiara
RECRUITING

Pisa, 56126, Italy

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Barbara Ann Karmanos Cancer Institute
TERMINATED

Detroit, Michigan, 48201, United States
Centre Antoine-Lacassagne
NOT_YET_RECRUITING

Nice, 06189, France

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Centre Leon Berard
RECRUITING

Lyon, 69008, France

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Centro Ricerche Cliniche di Verona s.r.l.
RECRUITING

Verona, 37134, Italy

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Dana-Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States

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Ellison Clinic at Saint John's
NOT_YET_RECRUITING

Los Angeles, California, 90064, United States

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Erasmus MC
RECRUITING

Rotterdam, 3015GD, Netherlands

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Florida Cancer Specialists ORLANDO/DDU
COMPLETED

Lake Mary, Florida, 32746, United States
Fondazione IRCCS San Gerardo dei Tintori
RECRUITING

Monza, 20900, Italy

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Fondazione Policlinico Universitario Agostino Gemelli
RECRUITING

Roma, 168, Italy

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Gustave Roussy
RECRUITING

Villejuif, 94805, France

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Hospital Clinico San Carlos
RECRUITING

Madrid, 28040, Spain

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Hospital Quiron Barcelona
RECRUITING

Barcelona, 08023, Spain

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Hospital San Pedro
RECRUITING

Logroño, 26006, Spain

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Hospital Universitari Sant Joan de Reus
RECRUITING

Reus, 43204, Spain

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Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain

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Hospital Universitario Fundación Jiménez Díaz
RECRUITING

Madrid, 28040, Spain

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Hospital Universitario HM Sanchinarro
RECRUITING

Madrid, 28050, Spain

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Hospital Universitario Quironsalud Madrid
RECRUITING

Pozuelo de Alarcón, 28223, Spain

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Hospital Universitario Virgen Macarena
RECRUITING

Seville, 41009, Spain

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Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest
RECRUITING

Bordeaux, 33000, France

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Institut Claudius Regaud
RECRUITING

Toulouse, 31059, France

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Institut Jules Bordet
NOT_YET_RECRUITING

Anderlecht, 1070, Belgium

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Institut Paoli-Calmettes
NOT_YET_RECRUITING

Marseille, 13009, France

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Instituto Oncologico Dr Rosell (IOR)
RECRUITING

Barcelona, 08028, Spain

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Istituto Europeo di Oncologia
RECRUITING

Milan, 20141, Italy

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Istituto Nazionale per lo Studio e la Cura dei Tumori
RECRUITING

Milan, 20133, Italy

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Kansai Medical University Hospital
RECRUITING

Hirakata, 573-1191, Japan

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Kyoto University Hospital
RECRUITING

Kyoto, 606-8507, Japan

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Louisiana State University Health Sciences Center
RECRUITING

New Orleans, Louisiana, 70112, United States

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MD Anderson Cancer Center
RECRUITING

Madrid, 28033, Spain

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Mary Crowley Cancer Research Center
COMPLETED

Dallas, Texas, 75230, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

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Mater Misericordiae Hospital
RECRUITING

Dublin, Ireland

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Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States

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Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States

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National Hospital Organization Kyushu Cancer Center
RECRUITING

Fukuoka, 811-1395, Japan

Contact Phone: •••-•••-••••

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Netherlands Cancer Institute
RECRUITING

Amsterdam, 1066CX, Netherlands

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Ospedale Santa Maria delle Croci
NOT_YET_RECRUITING

Ravenna, 48121, Italy

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Providence Cancer Institute Franz Clinic
RECRUITING

Portland, Oregon, 97213, United States

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START Midwest
RECRUITING

Grand Rapids, Michigan, 49546, United States

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START Mountain Region
RECRUITING

West Valley City, Utah, 84119, United States

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START San Antonio
RECRUITING

San Antonio, Texas, 78229, United States

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Saint Luke's Cancer Institute
RECRUITING

Kansas City, Missouri, 64111-3220, United States

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Sarah Cannon Research Institute
RECRUITING

Nashville, Tennessee, 37203, United States

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South Texas Accelerated Research Therapeutics (START) Barcelona- HM Nou Delfos
RECRUITING

Barcelona, 08023, Spain

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Spedali Civili di Brescia
NOT_YET_RECRUITING

Brescia, 25123, Italy

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Stefanie Spielman Comprehensive Breast Center
RECRUITING

Columbus, Ohio, 43212, United States

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Texas Oncology-Baylor Charles A. Sammons Cancer Center
RECRUITING

Dallas, Texas, 75246-2092, United States

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The Cancer Institute Hospital of JFCR
RECRUITING

Kōtō City, 135-8550, Japan

Contact Phone: •••-•••-••••

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The West Clinic, PLLC dba West Cancer Center
RECRUITING

Germantown, Tennessee, 38138, United States

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UCSF Medical Center at Mission Bay
RECRUITING

San Francisco, California, 94143, United States

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UH Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States

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USO-Virginia Cancer Specialists, PC
RECRUITING

Fairfax, Virginia, 22031, United States

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UZ Leuven
NOT_YET_RECRUITING

Leuven, 3000, Belgium

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University of Colorado Cancer Center
RECRUITING

Aurora, Colorado, 80045, United States

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University of Iowa
RECRUITING

Iowa City, Iowa, 52242, United States

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University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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University of Texas Southwestern
NOT_YET_RECRUITING

Dallas, Texas, 75390, United States

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University of Vermont Medical Center
NOT_YET_RECRUITING

Burlington, Vermont, 05401, United States

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Universitätsklinikum Erlangen
NOT_YET_RECRUITING

Erlangen, 91054, Germany

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Universitätsmedizin Mannheim
NOT_YET_RECRUITING

Mannheim, 68167, Germany

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Washington University
RECRUITING

St Louis, Missouri, 63110, United States

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Winship Cancer Institute, Emory University
RECRUITING

Atlanta, Georgia, 30322, United States

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Yale-New Haven Hospital
COMPLETED

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

BREAST CANCER SOLID TUMORS, ADULT