Could COPD drug help control blood sugar? new study explores
NCT ID NCT02363335
First seen Jun 26, 2026 · Last updated Jul 29, 2026 · Updated 4 times
Summary
This completed Phase 1 trial studied how two drugs, roflumilast (used for COPD) and sitagliptin (used for diabetes), affect blood sugar and gut hormones in 29 healthy volunteers aged 21-55. Participants received each drug alone, together, or a placebo, then drank a nutritional shake to measure hormone responses. The goal was to understand how these drugs might lower blood sugar, which could lead to new treatments for type 2 diabetes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Roflumilast and Sitagliptin
- What this could lead to
- If successful, this research could point toward new treatments for type 2 diabetes by better understanding how these drugs affect blood sugar and gut hormones.
- What could go wrong
- This is a small, early-phase study in healthy volunteers, not people with diabetes. The results may not apply to patients or lead to a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Institute of Aging, Clinical Research Unit
Baltimore, Maryland, 21224, United States
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