Brain scans after stroke may unlock secrets of cognitive decline
NCT ID NCT05089331
First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study follows 250 people who had a type of stroke called intracerebral hemorrhage (ICH) to understand why some experience progressive cognitive decline. Participants undergo advanced brain scans and tests of thinking and movement at 12–24 months after their stroke, with follow-up assessments over the next year. Researchers will also analyze blood samples for signs of inflammation that might be linked to worsening brain function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could reveal why some people experience progressive cognitive decline after a hemorrhagic stroke and point toward ways to predict or prevent it.
- What could go wrong
- This is an observational study, not a treatment trial. It may identify patterns but cannot prove cause and effect, and results may not apply to all stroke survivors.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baptist Health Louisville
Louisville, Kentucky, 40207, United States
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Columbia University
New York, New York, 10032, United States
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Duke University
Durham, North Carolina, 27710, United States
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Houston Methodist
Houston, Texas, 77030, United States
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University of Cincinnati
Cincinnati, Ohio, 45267, United States
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University of Illinois Chicago
Chicago, Illinois, 60612, United States
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University of Maryland
Baltimore, Maryland, 21201, United States
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