Mind over sickle cell: can stress relief ease the pain?

NCT ID NCT07316478

Recruiting now Symptom relief Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a stress management and mindfulness program can improve quality of life for adults with sickle cell disease. The program includes techniques from cognitive-behavioral therapy, relaxation exercises, and mindfulness meditation. Researchers will enroll 50 participants who live within 90 minutes of Philadelphia to see if the program helps with pain, mood, and daily function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Stress management and mindfulness program (behavioral intervention)
What this could lead to: If it works, this could offer a low-risk way to help people with sickle cell disease feel better day-to-day and manage stress.
What could go wrong: This is a small, early-stage trial with only 50 people, so results may not apply to everyone. The program is behavioral, not a medical treatment, so it won't cure the disease.

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Conditions

The condition(s) this trial relates to.

sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SICKLE CELL DISEASE

Contacts and locations

Locations

University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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