BREAKING: could some breast cancer patients finally take a break from treatment?
NCT ID NCT05721248
First seen Feb 20, 2026 · Last updated May 14, 2026 · Updated 5 times
Summary
This study looks at whether people with HER2-positive metastatic breast cancer who have had an excellent response to treatment (cancer controlled for 3+ years) can safely stop their anti-HER2 therapy. Researchers will monitor how long it takes for the cancer to progress in those who stop versus those who continue treatment. The goal is to see if a treatment break is possible without harming outcomes.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
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DFCI @ Foxborough
Foxborough, Massachusetts, 02035, United States
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DFCI @ Merrimack Valley
Methuen, Massachusetts, 01844, United States
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DFCI @ Milford Regional Hospital
Milford, Massachusetts, 01757, United States
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DFCI @ South Shore Hospital
South Weymouth, Massachusetts, 02190, United States
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Dana-Farber Cancer Insitute
Boston, Massachusetts, 02215, United States
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Duke University
Durham, North Carolina, 27710, United States
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Fred Hutchinson Cancer Center
Seattle, Washington, 98109, United States
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Georgetown University Medical Center
Washington D.C., District of Columbia, 02809, United States
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Mayo Clinic Hospital Arizona
Phoenix, Arizona, 85054, United States
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Mayo Clinic Rochester
Rochester, Minnesota, 55905, United States
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Mayo Clinical Hospital Florida
Jacksonville, Florida, 32224, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
Conditions
Explore the condition pages connected to this study.