Stool DNA test may offer easier cancer monitoring
NCT ID NCT04624555
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a stool DNA test (mt-sDNA) can accurately detect polyps or cancer in people who have already been treated for stage I-III colorectal cancer. Researchers will compare the stool test results to colonoscopy findings in 50 survivors. The goal is to see if the stool test is a reliable and acceptable alternative for routine surveillance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Multi-target stool DNA (mt-sDNA) test
- What this could lead to
- If successful, this stool test could offer a less invasive way to monitor colorectal cancer survivors for recurrence, potentially reducing the need for frequent colonoscopies.
- What could go wrong
- This is a small early study with only 50 participants, so results may not apply to everyone. The stool test may miss some polyps or cancers, leading to false reassurance.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
RECRUITINGCleveland, Ohio, 44106, United States
Contact Email: •••••@•••••
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