Stool DNA test may offer easier cancer monitoring

NCT ID NCT04624555

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a stool DNA test (mt-sDNA) can accurately detect polyps or cancer in people who have already been treated for stage I-III colorectal cancer. Researchers will compare the stool test results to colonoscopy findings in 50 survivors. The goal is to see if the stool test is a reliable and acceptable alternative for routine surveillance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Multi-target stool DNA (mt-sDNA) test

What this could lead to

If successful, this stool test could offer a less invasive way to monitor colorectal cancer survivors for recurrence, potentially reducing the need for frequent colonoscopies.

What could go wrong

This is a small early study with only 50 participants, so results may not apply to everyone. The stool test may miss some polyps or cancers, leading to false reassurance.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colon adenocarcinoma colonic neoplasm colorectal cancer colorectal carcinoma colorectal neoplasm rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••