Stool DNA test may offer easier cancer monitoring

NCT ID NCT04624555

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a stool DNA test (mt-sDNA) can accurately detect polyps or cancer in people who have already been treated for stage I-III colorectal cancer. Researchers will compare the stool test results to colonoscopy findings in 50 survivors. The goal is to see if the stool test is a reliable and acceptable alternative for routine surveillance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Multi-target stool DNA (mt-sDNA) test
What this could lead to
If successful, this stool test could offer a less invasive way to monitor colorectal cancer survivors for recurrence, potentially reducing the need for frequent colonoscopies.
What could go wrong
This is a small early study with only 50 participants, so results may not apply to everyone. The stool test may miss some polyps or cancers, leading to false reassurance.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Email: •••••@•••••

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