New antibiotic beads aim to heal bone infections in bedsores

NCT ID NCT06283979

Recruiting now Disease control Sponsor: Biocomposites Ltd Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase II trial tests whether placing antibiotic-releasing beads (STIMULAN VG) into the wound during surgery, plus standard antibiotics, works better than standard care alone for bone infections linked to stage IV pressure ulcers. About 60 adults will be randomly assigned to one of two groups. Success is measured by complete wound closure at 8 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: STIMULAN VG (a calcium sulfate bead that releases antibiotics locally)
What this could lead to: If successful, this could offer a more effective way to treat bone infections in severe pressure ulcers, potentially reducing the need for repeat surgeries.
What could go wrong: This is a small Phase II trial with only 60 participants, so results may not apply to everyone. The treatment involves surgery and antibiotics, which carry risks like infection or allergic reaction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

decubitus ulcer osteomyelitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOMYELITIS PRESSURE ULCER, STAGE IV

Contacts and locations

Locations

Advanced Foot Care, LLC
RECRUITING

Phoenix, Arizona, 85032, United States
Henry Ford Hospital
RECRUITING

Detroit, Michigan, 48202, United States
Missouri Orthopaedic Institute
RECRUITING

Columbia, Missouri, 65201, United States
NYU Langone Hospital - Long Island Clinical Research Center
RECRUITING

Mineola, New York, 11501, United States
Northwestern University Feinberg School of Medicine
RECRUITING

Chicago, Illinois, 60611, United States
Rutgers New Jersey Medical School
RECRUITING

Newark, New Jersey, 07103, United States
University of Mississippi Medical Center
RECRUITING

Jackson, Mississippi, 39216, United States
University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States
University of Pittsburgh, McGowan Institute for Regenerative Medicine
RECRUITING

Pittsburgh, Pennsylvania, 15219, United States

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