Cure My Disease

Don't miss your cure!

 Log in / Sign up

Local memories may help heal the brain after severe injury

NCT ID NCT07718321

Knowledge-focused Sponsor: Alfonso Magliacano Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This pilot study tests whether StimolIrpinia, a multimedia collection of local images, videos, and cultural information, can support cognitive rehabilitation in people with severe acquired brain injury. Ten hospitalized patients will use the tool in six 30-minute sessions over two weeks, alongside their usual rehab. The study focuses on whether the tool is usable and acceptable to both patients and therapists.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
StimolIrpinia-supported cognitive rehabilitation activities
What this could lead to
If successful, StimolIrpinia could offer a personalized, culturally relevant way to support cognitive recovery after severe brain injury.
What could go wrong
This is a very small pilot study with only 10 patients, so results may not apply broadly. The tool is not a medical device and is meant to assist, not replace, standard rehabilitation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 10 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Patients With Severe Acquired Brain Injury - Inclusion Criteria * Age between 18 and 75 years. * Level of Cognitive Functioning (LCF) score \>= 5 at study entry. * Stable clinical diagnosis, assessed by at least four repeated LCF evaluations within a 1-week time window. * History of severe acquired brain injury of traumatic, anoxic, vascular, or mixed etiology, defined as Glasgow Coma Scale score \<= 8 for at least 24 hours after brain injury. * Pathological performance on at least one Oxford Cognitive Screening (OCS) subscale. * Having lived for a prolonged period in the Irpinia area, including Partenio, Valle Ufita-Baronia, Serinese-Solofrana, Alta Irpinia, Vallo di Lauro-Baianese, and/or Terminio-Cervialto. * Written informed consent signed by the patient or by the patient's legal representative. Patients With Severe Acquired Brain Injury - Exclusion Criteria • Severe medical conditions that may prevent participation in rehabilitation sessions, including severe language deficits incompatible with understanding instructions, severe cardiovascular instability, photosensitive or reflex epilepsy, and disabling visual or hearing deficits. Rehabilitation Professionals/Operators - Inclusion Criteria * Age \>= 18 years. * Proven experience in neuromotor and/or cognitive rehabilitation of patients with severe acquired brain injury. * Written informed consent to participate in the study. Rehabilitation Professionals/Operators - Exclusion Criteria • Participation in the development of the StimolIrpinia repository, resulting in prior familiarity with the repository.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Cognitive impairment are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

brain injury Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive impairment Cognitive rehabilitation Neurorehabilitation Severe acquired brain injury

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Polo Specialistico Riabilitativo Fondazione Don Gnocchi

    RECRUITING

    Sant'Angelo dei Lombardi, AV, 83054, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.