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AI tailors brain workouts: a new hope for cognitive decline?

NCT ID NCT07788209

Disease control Sponsor: Xuanwu Hospital, Beijing Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time

Summary

This study looks at whether an AI-powered, personalized brain-training program can improve cognitive function in adults with mild cognitive impairment. Participants used a tablet-based program that adapts tasks and difficulty to each person's performance. The study compares this adaptive approach to a standard, non-AI training program to see which is more effective at enhancing memory, attention, and other thinking skills over 8 weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
AI-based adaptive computerized cognitive training (CCT) delivered on a tablet
What this could lead to
If successful, this could point toward more effective, personalized brain-training programs to help people with cognitive impairment improve memory and thinking.
What could go wrong
This is a retrospective study, not a controlled experiment, so results may be influenced by other factors. The training's benefits may not last or may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 516 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population included patients with cognitive impairment who had received an 8-week tablet-based computerized cognitive training program at Xuanwu Hospital between October 2021 and May 2024. Participants were categorized into three groups according to the training recommendation strategy they actually received.

Ages

45 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age ≥ 45 years; * a Montreal Cognitive Assessment (MoCA) score between 10 and 25; * were able to communicate in Mandarin. Exclusion Criteria: * no completion of at least 8 weeks of training; * no engagement in training for ≥ 60 minutes per week; * diagnosis of depression or other psychiatric disorders; * diagnosis of systemic diseases, such as hepatic or renal dysfunction, endocrine disorders, or vitamin deficiencies.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive impairment

Contacts and locations

Locations

  • Xuanwu Hospital, Capital Medical University

    Beijing, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.