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Sticky bone vs chitosan: which graft better saves the jaw ridge after tooth extraction?

NCT ID NCT07826377

Symptom relief Sponsor: Damascus University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

After a tooth is pulled, the jawbone can shrink, which makes placing a dental implant later more difficult. This study compares two grafting materials, sticky bone (made from the patient's blood and bone graft) and chitosan mixed with bone graft, to see which better preserves the ridge. Researchers will measure changes in ridge width and height using CT scans taken right after surgery and four months later in 12 adults.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
sticky bone graft made from the patient's blood and bone graft material, compared with chitosan combined with bone graft
What this could lead to
If one approach preserves the jaw ridge better, dentists could use it to make dental implant placement easier after tooth extraction.
What could go wrong
This is a small study of 12 people, so the results may not apply broadly. Grafting procedures carry risks of infection, swelling, or the graft not integrating as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 12 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adults aged 18 to 65 years. 2. Systemically healthy or with mild systemic disease classified as ASA physical status I-II. 3. Clinical indication for extraction of two contralateral, symmetrical single-rooted teeth in the maxilla or mandible, with extraction not indicated because of periodontal disease. 4. Intact alveolar socket walls following extraction, including the buccal, lingual/palatal, mesial, and distal walls, confirmed clinically after extraction and supported by preoperative CBCT assessment. 5. A minimum width of 2 mm of keratinized tissue at each planned extraction site. 6. Good oral hygiene, defined as an O'Leary Plaque Control Record of less than 25%. Exclusion Criteria: 1. Uncontrolled systemic diseases or conditions that may adversely affect bone metabolism or healing, including uncontrolled diabetes mellitus, hyperparathyroidism, or treatment with bisphosphonates, particularly intravenous administration. 2. Previous radiotherapy to the head and neck region. 3. Immunosuppression, including active chemotherapy or long-term treatment with high-dose systemic corticosteroids. 4. Pregnancy or breastfeeding. 5. Multirooted teeth, including molars or teeth with root furcation involvement. 6. Known allergy or hypersensitivity to bovine collagen, if a bovine-derived bone graft is used, or to chitosan or shellfish products such as shrimp. 7. Acute infection or a purulent abscess at the extraction site, or a large periapical lesion. 8. Presence of buccal bone dehiscence or fenestration at the planned extraction site. 9. Current smoking. 10. Untreated or inadequately controlled periodontal disease.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar ridge preservation

How to take part

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