Cure My Disease

Don't miss your cure!

 Log in / Sign up

A simple arm injection may quiet a mysterious chronic cough

NCT ID NCT06634823

Symptom relief Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This trial investigates whether a single steroid injection into the arm muscle can reduce symptoms of unexplained chronic cough. About 40 adults with chronic cough that has no clear cause will receive either the steroid or a placebo injection. Researchers will track changes in cough severity and quality of life over several weeks to see if this easy-to-administer treatment offers real relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a steroid injection (triamcinolone acetonide) into the arm muscle
What this could lead to
If effective, this could offer a simple, widely accessible treatment option for people with unexplained chronic cough.
What could go wrong
This is a very early-phase trial with only 40 participants. The steroid may not work better than placebo, and side effects from steroids are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2024

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * History consistent with chronic unexplained or refractory cough * Age ≥ 18 Exclusion Criteria: * Current smokers * Uncontrolled diabetes (A1c\>7%) * Patients on ACE inhibitors or Angiotensin II receptor blockers (ARBs) * Abnormal pulmonary function testing (PFTs) since start of the cough * Patients with uncontrolled obstructive sleep apnea * Abnormal chest X-ray within past 6 months * Uncontrolled reflux * Prior superior laryngeal nerve injection * Current neuromodulating medication use for chronic cough\*

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Chronic cough (CC) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Chronic Cough Cough laryngeal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic cough (CC) Coughing Laryngeal disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29403, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.