Step up: a new program aims to boost daily steps and reduce disability in blood cancer survivors.

NCT ID NCT06575712

Recruiting now Symptom relief Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times

Summary

This study tests a program called Step Up that combines in-person coaching with a mobile app to teach coping skills and encourage physical activity. It includes 177 adults who have had a stem cell transplant or CAR-T therapy for blood cancers like leukemia or multiple myeloma. The goal is to see if the program helps reduce physical disability and improve walking ability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: coping skills training and activity coaching (Step Up program)
What this could lead to: If it works, this program could help blood cancer survivors feel less disabled and more active after intensive treatments like transplant or CAR-T therapy.
What could go wrong: This is a behavioral intervention study, not a drug trial, so benefits may be modest. Results depend on patient engagement and may not apply to everyone.

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Conditions

The condition(s) this trial relates to.

hematopoietic and lymphoid cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CAR-T CELL THERAPY HEMATOPOIETIC STEM CELL TRANSPLANT

Contacts and locations

Locations

Duke Cancer Institute
RECRUITING

Durham, North Carolina, 27705, United States

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