Fat stem cells injected into fingers aim to heal scleroderma ulcers

NCT ID NCT04356755

First seen Jan 06, 2026 · Last updated Jun 22, 2026 · Updated 26 times

Summary

This phase 2 trial tests whether injecting stem cells from fat tissue directly into finger ulcers can help them heal in people with scleroderma. The study will compare the stem cell treatment to a placebo in 32 adults who have at least one painful, non-healing finger sore. The goal is to see if the stem cells can close the wound and prevent it from coming back without serious side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Toulouse - Hôpital PURPAN-TSA

    RECRUITING

    Toulouse, 31059, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Grenoble Hospital

    NOT_YET_RECRUITING

    Grenoble, France

    Contact

  • Lille Hopsital

    NOT_YET_RECRUITING

    Lille, France

    Contact

  • Marseille Hospital

    NOT_YET_RECRUITING

    Marseille, France

    Contact

  • Montpellier Hospital

    NOT_YET_RECRUITING

    Montpellier, France

    Contact

  • Nantes Hospital

    NOT_YET_RECRUITING

    Nantes, France

    Contact

  • Poitiers Hospital

    NOT_YET_RECRUITING

    Poitiers, France

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cultured adipose-derived stem cells (AdMSC)

What this could lead to

If it works, this could offer a new way to heal stubborn finger ulcers in scleroderma, improving hand function and quality of life.

What could go wrong

This is a small early-phase trial with only 32 participants. The treatment may not heal ulcers better than placebo, and there are risks like infection or worsening of the ulcer.

Conditions

The condition(s) this trial relates to.

systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.