Could stem cells shield kidneys after severe injury?

NCT ID NCT06654193

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether stem cells from donated fat tissue can prevent kidney injury from getting worse in people who have been severely hurt in accidents or burns. About 70 ICU patients will receive either stem cells or a placebo. The goal is to see if the treatment is safe and helps kidneys recover faster, reducing the need for dialysis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Allogeneic adipose-derived mesenchymal stem cells (HB-adMSCs)

What this could lead to

If it works, this could point toward a treatment that prevents acute kidney injury from getting worse after severe trauma or burn, reducing the need for dialysis.

What could go wrong

This is an early Phase 1/2 trial with only 70 participants, so results are preliminary. Stem cell infusions carry risks like allergic reactions or infection, and the treatment may not improve kidney function.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE KIDNEY INJURY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Alabama at Birmingham

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact

    Contact

    Contact

  • University of California, San Francisco

    NOT_YET_RECRUITING

    San Francisco, California, 94143, United States

    Contact

    Contact

    Contact

    Contact

    Contact

  • University of Texas Health Science Center at Houston (UTHealth Houston)

    RECRUITING

    Houston, Texas, 77479, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact

    Contact