Stem cell shot for Crohn's pouch fistulas shows early promise but study halted

NCT ID NCT05075811

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tested whether injecting stem cells from donor bone marrow could safely heal fistulas (abnormal tunnels) in people with Crohn's disease who have a J-pouch after colon removal. The study aimed to see if the treatment could close the fistulas and improve symptoms. It was terminated early, so results are limited.

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Conditions

The condition(s) this trial relates to.

Fistula ileal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States