Radical reset vs. standard drugs: the fight to control a severe autoimmune disease
NCT ID NCT04464434
Summary
This study aimed to find the best initial treatment for people recently diagnosed with a severe, fast-moving form of scleroderma. It compared two approaches: an aggressive stem cell transplant right away versus starting with standard immunosuppressive drugs and saving the transplant as a backup option. The goal was to see which strategy better helps patients survive without major organ damage and improves their skin, lung function, and quality of life.
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Contacts and locations
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Locations
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Amsterdam Rheumatology Centre
Amsterdam, Netherlands
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Gaetano Pini-CTO
Milan, Italy
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Ospedale San Raffaele
Milan, Italy
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Radboudumc Nijmegen
Nijmegen, Netherlands
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Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield, United Kingdom
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University Hospital Rome
Roma, Italy
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University Medical Centre Leiden
Leiden, Netherlands
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University Medical Centre Utrecht
Utrecht, Netherlands
Conditions
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