Half-Matched stem cell transplant offers hope for severe sickle cell disease

NCT ID NCT03121001

First seen Jan 26, 2026 · Last updated May 16, 2026 · Updated 15 times

Summary

This study tests a stem cell transplant using a half-matched family donor for people with severe sickle cell disease. Participants receive low-dose radiation and chemotherapy before the transplant, followed by drugs to prevent rejection. The main goal is to see if the donor cells start making healthy blood cells by day 60. About 50 people will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Illinois at Chicago

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.