Immune reset: stem cell trial offers hope for young people with deadly autoimmune diseases
NCT ID NCT05029336
First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 30 times
Summary
This study tests a stem cell transplant to 'reset' the immune system in children and young adults (ages 8–25) with life-threatening lupus or scleroderma that hasn't responded to standard treatments. The approach uses high-dose therapy to wipe out faulty immune cells, then infuses the patient's own stem cells to rebuild a healthy immune system. The main goal is to see if this can stop the disease from progressing for at least two years.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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