Own stem cells may heal scarred vocal cords and restore voice
NCT ID NCT04290182
First seen Feb 02, 2026 · Last updated Jun 23, 2026 · Updated 27 times
Summary
This early-phase trial tested whether injecting a patient's own stem cells into scarred vocal folds could safely improve severe hoarseness. Nine adults with untreatable voice problems received the stem cell injection during surgery. Researchers monitored side effects and voice function for one year to see if the treatment was safe and could help restore their voice.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Karolinska Trial Alliance
Stockholm, Stockholm County, 11324, Sweden
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
patient's own mesenchymal stromal cells (stem cells)
What this could lead to
If it works, this could offer a lasting treatment for severe hoarseness caused by vocal fold scarring, where no effective options exist today.
What could go wrong
This is a very early, small trial (9 people) with no control group, so results may not apply widely. The treatment is also surgical, with inherent risks.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.