A squirt of steroid during surgery may stop voice loss
NCT ID NCT07722091
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This trial tests whether spraying the steroid dexamethasone onto nerve-rich areas in the abdomen during upper abdominal surgery can prevent hoarseness afterward. About 584 adults having elective gastric, liver, or pancreatic surgery will be randomly assigned to receive either the steroid spray or a placebo at the end of the operation. Their voices will be assessed daily for 10 days to see if the treatment reduces the rate of hoarseness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dexamethasone sprayed onto nerve-rich areas in the abdomen during surgery
- What this could lead to
- If effective, this simple, low-cost technique could become a standard step during abdominal surgery to prevent postoperative hoarseness.
- What could go wrong
- This is a single-center trial, and the effect may not be large or generalizable. Dexamethasone is generally safe, but spraying it near nerves carries unknown risks.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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