Could stem cells ease your back pain without surgery?

NCT ID NCT03737461

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 29 times

Summary

This study tests whether a single injection of donor stem cells into the spinal disc can reduce pain and improve function in people with chronic low back pain from degenerative disc disease. About 113 adults aged 18–60 who have not responded to standard treatments will receive either the stem cells or a sham injection. The main goal is to see if the treatment provides meaningful pain relief and better mobility after 12 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • APHP Cochin

    Paris, France

  • BG Klinikum Bergmannstrost

    Halle, 06112, Germany

  • CHU Saint Antoine

    Paris, 75012, France

  • CHU de Nantes

    Nantes, France

  • Campus Bio-Medico University of Rome

    Roma, 00128, Italy

  • Clínica Universidad de Navarra

    Pamplona, 31008, Spain

  • Hospital Sagrado Corazón Valladolid

    Valladolid, 47002, Spain

  • Institut de Teràpia Regenerativa Tissular

    Barcelona, 08022, Spain

  • UH Montpellier

    Montpellier, 34295, France

Conditions

Explore the condition pages connected to this study.