Could stem cells ease stubborn back pain? new trial tests injection therapy
NCT ID NCT03737461
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This clinical trial tests whether injecting stem cells into the spinal discs can reduce pain and improve function in people with chronic low back pain from degenerative disc disease. About 113 adults aged 18-60 who haven't gotten relief from standard treatments will receive either a stem cell injection or a sham procedure. Researchers will measure pain levels and disability after 12 months to see if the stem cells make a difference.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
allogeneic bone marrow-derived mesenchymal stem cells (BM-MSCs)
What this could lead to
If it works, this could offer a new treatment option for people with chronic low back pain that hasn't improved with standard care.
What could go wrong
This is an early-to-mid stage trial with only 113 participants. The stem cell injection may not provide lasting pain relief, and there are risks like infection or nerve damage from the injection procedure.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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APHP Cochin
Paris, France
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BG Klinikum Bergmannstrost
Halle, 06112, Germany
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CHU Saint Antoine
Paris, 75012, France
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CHU de Nantes
Nantes, France
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Campus Bio-Medico University of Rome
Roma, 00128, Italy
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Clínica Universidad de Navarra
Pamplona, 31008, Spain
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Hospital Sagrado Corazón Valladolid
Valladolid, 47002, Spain
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Institut de Teràpia Regenerativa Tissular
Barcelona, 08022, Spain
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UH Montpellier
Montpellier, 34295, France