Massive global study aims to speed up TB diagnosis at local clinics

NCT ID NCT05845112

Completed Diagnosis Sponsor: Liverpool School of Tropical Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested several tuberculosis (TB) diagnostic tools in over 14,000 people across seven countries. The goal was to find tests that are accurate enough to use in local clinics, without needing special lab equipment. Researchers looked at a simple blood test for C-reactive protein (CRP) and other combinations to see which works best for different groups, including people with HIV and children.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: C-Reactive Protein (CRP) point-of-care test
What this could lead to: If successful, this could lead to simpler, more accurate TB tests that work in local clinics, helping more people get diagnosed and treated sooner.
What could go wrong: This is a diagnostic accuracy study, not a treatment trial. Even if tests perform well, they still need to be rolled out and used effectively in real-world settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

disease tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIAGNOSIS TUBERCULOSIS

Contacts and locations

Locations

CHPR

Bamenda, Cameroon
Friends for International TB Relief

Hà Nội, Vietnam
Fundação de Apoio à Pesquisa e Extensão de Sergipe

Sergipe, Brazil
Icddr,B

Dhaka, Bangladesh
Janna Health Foundation

Adamawa, Nigeria
KEMRI

Kisumu, Kenya
Malawi-Liverpool-Wellcome Clinical

Blantyre, Malawi
Zankli Research Centre, Bingham University

Abuja, Nigeria

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