Massive global study aims to speed up TB diagnosis at local clinics

NCT ID NCT05845112

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested several tuberculosis (TB) diagnostic tools in over 14,000 people across seven countries. The goal was to find tests that are accurate enough to use in local clinics, without needing special lab equipment. Researchers looked at a simple blood test for C-reactive protein (CRP) and other combinations to see which works best for different groups, including people with HIV and children.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

C-Reactive Protein (CRP) point-of-care test

What this could lead to

If successful, this could lead to simpler, more accurate TB tests that work in local clinics, helping more people get diagnosed and treated sooner.

What could go wrong

This is a diagnostic accuracy study, not a treatment trial. Even if tests perform well, they still need to be rolled out and used effectively in real-world settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

disease tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHPR

    Bamenda, Cameroon

  • Friends for International TB Relief

    Hà Nội, Vietnam

  • Fundação de Apoio à Pesquisa e Extensão de Sergipe

    Sergipe, Brazil

  • Icddr,B

    Dhaka, Bangladesh

  • Janna Health Foundation

    Adamawa, Nigeria

  • KEMRI

    Kisumu, Kenya

  • Malawi-Liverpool-Wellcome Clinical

    Blantyre, Malawi

  • Zankli Research Centre, Bingham University

    Abuja, Nigeria