Could a smaller surgery spare medullary thyroid cancer patients from lifelong pills?
NCT ID NCT07612293
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether removing only the cancerous part of the thyroid and nearby lymph nodes on one side is safe and effective for sporadic medullary thyroid cancer. Currently, all patients get the entire thyroid removed, which requires lifelong hormone pills and carries higher risks. The trial will enroll 100 adults to see if the less extensive surgery leads to remission and avoids the need for a second surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Thyroid lobectomy with ipsilateral central neck dissection
- What this could lead to
- If successful, this could offer a less invasive surgical option for sporadic medullary thyroid cancer, avoiding lifelong thyroid hormone pills and reducing complication risks.
- What could go wrong
- This is an early-stage trial with only 100 participants. It may not prove that the less extensive surgery is as effective as total thyroidectomy, and some patients may still need a second surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SPORADIC MEDULLARY THYROID CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, 90095, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New PET tracer could spot cancers that standard scans overlook
- New decision aid empowers thyroid cancer patients to choose their care path
- New PET scan aims to spot hidden cancers with precision
- New hope for kids with rare cancers: drug targets tumor growth
- Targeted drug before surgery shows promise for RET-Altered thyroid cancer