Diet showdown: three eating plans battle bloating in scleroderma patients

NCT ID NCT07402226

Recruiting now Symptom relief Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study compares three different diets to see which one best reduces bloating and other stomach symptoms in people with systemic sclerosis (scleroderma). Sixty participants will follow one of three diets for six weeks: a low-FODMAP diet, a diet that removes foods harmful to the gut, or a diet focused on regular meals and fiber. The goal is to find a practical way to improve quality of life without medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dietary intervention (low FODMAP, CDED, or NICE diet)
What this could lead to: If successful, this could point to a simple, drug-free way to manage bloating and stomach discomfort in people with systemic sclerosis.
What could go wrong: This is a small, early-stage trial with only 60 people. Diets are hard to stick to, and results may not apply to everyone. It tests symptom relief, not a cure.

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Conditions

The condition(s) this trial relates to.

systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYSTEMIC SCLEROSIS (SSC)

Contacts and locations

Locations

University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States

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