Heart scarring in HIV: researchers probe substance use link

NCT ID NCT07461350

First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times

Summary

This observational study will use cardiac MRI to examine how stimulant and polysubstance use affects heart scarring and inflammation in 400 people with and without HIV. Participants will have one study visit for a detailed heart scan. The goal is to better understand the combined impact of HIV and substance use on heart health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could reveal how substance use harms the heart in people with HIV, pointing toward better monitoring or prevention strategies.
What could go wrong
This is an observational study, not a treatment trial. It will not test any therapy, and results may not lead to direct changes in care.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Albert Einstein College of Medicine

    The Bronx, New York, 10462, United States

  • Emory University, School of Medicine

    Atlanta, Georgia, 30322, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21218, United States

  • University of California, San Francisco

    San Francisco, California, 94115, United States

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