Heart shield after pregnancy: spironolactone trial targets lasting hypertension

NCT ID NCT07041281

First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 30 times

Summary

This study tests whether taking spironolactone for three months after delivery can lower blood pressure and improve heart health in women who had preeclampsia or gestational hypertension. About 204 women with overweight or obesity before pregnancy will be randomly assigned to receive the drug or a placebo. The goal is to see if this short-term treatment can prevent long-term heart problems.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pittsburgh Magee-Womens Hospital

    NOT_YET_RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.