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Zapping a nerve inside the spine bone may ease chronic back pain

NCT ID NCT07696507

Not yet recruiting Symptom relief Sponsor: Axon srl Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This trial tests whether a device that uses controlled heat to target a nerve inside the spine bone can safely reduce disability and pain in adults with long-term low back pain. Participants must have had pain for at least 6 months and have specific changes on MRI. All receive the procedure, with no untreated comparison group, and are followed for 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Radiofrequency basivertebral nerve ablation device (Spinery® RF Generator and accessories)
What this could lead to
If successful, this could offer a new, minimally invasive option for people with chronic low back pain that hasn't improved with other treatments.
What could go wrong
This is an early study with no comparison group, so results may not prove the device works better than placebo or other treatments. Risks include procedure-related pain, infection, or nerve damage.

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Conditions

The condition(s) this trial relates to.

Low Back Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LOW BACK PAIN (CLBP) LOW BACK PAIN

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Ospedaliera Antonio Cardarelli - U.O.C. Neuroradiologia

    Naples, 80131, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Azienda Ospedaliera di Cosenza

    Cosenza, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale Santissima Trinità

    Cagliari, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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