Tiny gold seeds could sharpen radiation for spine tumors

NCT ID NCT01624220

Completed Knowledge-focused Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether implanting tiny gold markers near spinal tumors helps deliver radiation more accurately. Researchers also checked if giving slightly more radiation to the nearby esophagus is safe, which might improve tumor control. The study involved 41 adults with various cancers that had spread to the spine.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiation therapy (spinal SBRT) with gold seed implants
What this could lead to: If successful, this could lead to more precise radiation delivery for spinal tumors, potentially improving tumor control while keeping side effects manageable.
What could go wrong: This is a small, early-phase study with only 41 participants, so results may not apply broadly. Higher radiation doses to the esophagus carry risks like inflammation or injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast neoplasm digestive system neoplasm melanoma Neoplasms, Unknown Primary non-small cell lung carcinoma prostate cancer renal cell carcinoma sarcoma spinal cord cancer spinal cord neoplasm Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SPINAL TUMOR

Contacts and locations

Locations

University of Texas MD Anderson Cancer Center

Houston, Texas, 77030, United States

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