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Hands-On spine therapy may offer new hope for migraine sufferers

NCT ID NCT07774286

Symptom relief Sponsor: Borna Farhoomand Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 19, 2026 · Last updated Aug 26, 2026 · Updated 4 times

Summary

This study tests whether a type of hands-on physical therapy applied to the spine can reduce headache pain and improve daily function in women with episodic migraine. Ten women aged 18 to 30 will receive 10 sessions of spinal manual therapy over two weeks, with follow-up assessments after one month. The goal is to see if this approach can ease pain, reduce sensitivity, and improve movement control.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Multi-segmental spinal manual therapy (joint mobilizations and manipulations to the spine)
What this could lead to
If effective, this hands-on therapy could offer a drug-free option to reduce migraine pain and related disability in women.
What could go wrong
This is a very small early study with no control group, so results may not be reliable or generalizable. The therapy is generally safe but may cause temporary soreness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 10 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female patients aged 18-30 years, * Diagnosis of episodic migraine established by a specialist neurologist, * Headache frequency of \<15 days per month, * Pain intensity score of ≥40 mm on the Visual Analog Scale (VAS), * Absence of any diagnosed psychiatric disorders, * Literacy (ability to read and write), * Ability to communicate effectively without language or cognitive barriers, * Voluntary participation confirmed by signed written informed consent. Exclusion Criteria: * History of communication disorders or neuromusculoskeletal diseases that impede assessment procedures, * Headache frequency exceeding 15 days per month, * Diagnosis of other primary or secondary headache types (e.g., cervicogenic headache, tension-type headache), * Pregnancy, * Diagnosis of fibromyalgia syndrome or myofascial pain syndrome, * Diagnosis of systemic rheumatic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus), * Diagnosis or presence of symptoms related to spinal disc disorders (e.g., disc herniation, disc prolapse), * History of whiplash or similar cervical/head trauma, * Diagnosis or presence of symptoms associated with temporomandibular joint dysfunction (TMD), * Having received physical therapy within the last 3 months, * Having undergone anesthetic nerve block procedures within the last 6 months, * Receiving any prophylactic or interventional migraine therapy other than acute analgesics, * Self-reported history or presence of malignancy.

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Conditions

The condition(s) this trial relates to.

migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Migraine disorders

How to take part

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  1. The official record

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