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Your voice could hold the key to spotting lung disease

NCT ID NCT04754490

Diagnosis Sponsor: Cwm Taf University Health Board (NHS) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study investigates whether patterns in speech and breathing can indicate the presence of obstructive respiratory diseases like COPD. Researchers will collect short voice recordings from patients with and without lung disease and compare them to standard lung function tests. The goal is to build a database of speech patterns that could one day lead to a simple, non-invasive diagnostic tool.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple, non-invasive way to screen for or monitor chronic respiratory diseases using just a voice recording.
What could go wrong
This is a small, early-stage study focused on collecting data, not testing a treatment. The approach may not prove accurate enough for real-world diagnosis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

80 people

The number who actually took part.

Started

Mar 2019

Finished

Jun 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patient \>18 years old referred for spirometry in the Respiratory Physiology Clinic at Prince Charles Hospital; Eligibility Criteria - Control Participants Control participants will be contact through the British Lung Foundations local groups who have indicated their willingness to be involved in local clinical research to act as control participants. As all prospective participants will have had their respiratory function measured before taking part by a Respiratory Physiologist, we do not expect to have to screen for medical issues for participation in the study. Furthermore, the actual tests the participants will be undertaking will be non - invasive, submaximal and will require little or no effort.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

6.1.2 Inclusion criteria Patient Participants 1. Adult patient \>18 years old referred for spirometry in the Respiratory Physiology Clinic at Prince Charles Hospital; 2. Clinically defined obstructive or restrictive respiratory disease (indicated by spirometry) 3. Clinically stable (indicated by being able to undergo spirometry) 4. No significant unstable disease co-morbidities (indicated by being able to undergo spirometry) 5. Capable of providing informed consent. 6. Willing to take part in all study measurements. 7. The speaking exercise will be conducted in English on this study. 8. Participants are not taking part in any other research. 6.1.3 Inclusion criteria Control Participants 1\. No obstructive or restrictive respiratory disease (indicated by spirometry) 2. Clinically stable (indicated by being able to undergo spirometry) 3. No significant unstable disease co-morbidity's (indicated by being able to undergo spirometry) 4. Capable of providing informed consent. 5. Willing to take part in all study measurements. 6. The speaking exercise will be conducted in English on this study. 7. Participants are not taking part in any other research. 6.1.4 Exclusion criteria for both Patient and Control Participants 1. Any form of challenge testing in the Respiratory Physiology Department involving salbutamol. 2. Severe Sensory and/or Cognitive Impairment 3. Inability to complete study measurements

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset obstructive lung disease restrictive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD

Contacts and locations

Locations

  • Cwm Taf Morgannwg Health Board

    Abercynon, Wales, CF45 4SN, United Kingdom

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