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Swiss study seeks to unlock secrets of transgender health

NCT ID NCT06774053

Knowledge-focused Sponsor: University Hospital, Basel, Switzerland Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study follows 600 transgender and gender-diverse people in Switzerland to learn what affects their health and happiness during gender-affirming treatments. Participants fill out surveys, give blood and other samples, and have routine check-ups. The goal is to find out which factors lead to better outcomes, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 600 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Jan 2046

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The project population will consist of TGD individuals above age 16 who are diagnosed with gender incongruence and who wish medical transition or are on medical transition (at any stage of their transition, including individuals who interrupt/-ed medical transition or detransition/-ed). Recruitment for the study will initially take place at the University Hospital of Basel and the Cantonal Hospital of Luzern, with plans to expand to additional centers (e.g. University Hospital of Zurich, University Hospital of Geneva and Cantonal Hospital of St Gallen) as the study progresses. The study targets individuals at various stages of medical transition, including those initiating, continuing, or discontinuing gender-affirming therapies. Efforts will ensure inclusion of all gender identities to comprehensively address their unique healthcare needs.

Ages

16 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 16 years and above. * Established diagnosis of gender incongruence * Indication for gender affirming therapy or ongoing or discontinued gender affirming therapy Exclusion Criteria: * Unable to give informed consent * Missing commitment or ability to study protocol adherence

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Conditions

The condition(s) this trial relates to.

Gender Dysphoria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gender incongruence Transgender individuals

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Cantonal Hospital of Lucerne

    NOT_YET_RECRUITING

    Lucerne, 6000, Switzerland

  • University Hospital of Basel

    RECRUITING

    Basel, 4031, Switzerland

  • University Hospital of Zürich

    NOT_YET_RECRUITING

    Zurich, 8091, Switzerland

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