New study to uncover hidden heart risks of hormone therapy in transgender individuals

NCT ID NCT07394400

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study will follow 94 transgender individuals for 12 months to see how gender-affirming hormone therapy affects their mood, stress, and heart health. Researchers will measure inflammation, blood vessel function, and other markers to understand potential cardiovascular risks. The goal is to improve healthcare for transgender people by providing clearer information on the benefits and risks of hormone therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
gender-affirming hormone therapy
What this could lead to
If successful, this study could help doctors better understand the risks and benefits of hormone therapy for transgender individuals, leading to safer and more personalized care.
What could go wrong
This is an observational study, not a treatment trial. It will not prove cause and effect, and results may take years to influence medical guidelines.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Universitario Doctor Peset

    Valencia, Valencia, 46017, Spain

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Other studies related to the condition(s) this trial covers.