New study to uncover hidden heart risks of hormone therapy in transgender individuals
NCT ID NCT07394400
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This observational study will follow 94 transgender individuals for 12 months to see how gender-affirming hormone therapy affects their mood, stress, and heart health. Researchers will measure inflammation, blood vessel function, and other markers to understand potential cardiovascular risks. The goal is to improve healthcare for transgender people by providing clearer information on the benefits and risks of hormone therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
gender-affirming hormone therapy
What this could lead to
If successful, this study could help doctors better understand the risks and benefits of hormone therapy for transgender individuals, leading to safer and more personalized care.
What could go wrong
This is an observational study, not a treatment trial. It will not prove cause and effect, and results may take years to influence medical guidelines.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital Universitario Doctor Peset
Valencia, Valencia, 46017, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••