Bone scan boost: could Whole-Body SPECT sharpen radiation targeting for metastatic prostate cancer?
NCT ID NCT06439784
First seen Jul 24, 2026 · Last updated Jul 24, 2026
Summary
This trial explores whether a whole-body bone scan (SPECT/CT) taken in the treatment position can help doctors plan stereotactic radiotherapy more precisely for prostate cancer that has spread to the bones. Thirty patients will receive the scan in addition to standard imaging, and researchers will compare radiation plans created with and without the SPECT images. The goal is to see if the SPECT-based plans are equivalent or better, potentially allowing for more accurate targeting of tumors.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- whole-body SPECT/CT imaging using VERITON-CT CZT camera
- What this could lead to
- If SPECT/CT proves equivalent or superior to standard imaging, it could enable more precise radiotherapy planning and potentially better outcomes for prostate cancer patients with bone metastases.
- What could go wrong
- This is a small, early feasibility study with only 30 participants. The imaging technique may not translate into meaningful clinical benefits, and the results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years, * Good general health WHO ≤ 1 * Informed and signed consent prior to any specific study procedure. * Patient affiliated to the social security system * Bone metastases from prostate cancer * Indication for bone stereotactic radiotherapy Exclusion Criteria: * Presence of active cancer in the previous three years * Protected adults (under guardianship or curatorship) * Unable to undergo medical monitoring for geographical, social or psychological reasons * Unable to decubitus (orthopnea, etc.), * Hypersensitivity to HDP or to one of the excipients of the radiopharmaceutical. * History of radiotherapy of the volume to be treated by stereotaxy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centre Henri Becquerel
Rouen, 76038, France
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