New scanner could help surgeons spot Left-Behind cancer Mid-Operation

NCT ID NCT06676943

Completed Diagnosis Sponsor: University Hospitals Coventry and Warwickshire NHS Trust Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new type of PET-CT scanner that can scan a tumor right after it is removed from the body. Patients with prostate or head and neck cancer received a small amount of radioactive tracer before surgery, which sticks to cancer cells. After removal, the specimen was scanned to see if cancer cells reached the edge (margin). The scan results were compared to standard lab tests to see how accurate the new method is. If it works well, surgeons could use it during operations to make sure they remove all the cancer the first time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radioactive tracer (fluorodeoxyglucose or similar) injected before surgery
What this could lead to: If successful, this technique could help surgeons see during an operation whether they have removed all the cancer, reducing the need for extra treatments or second surgeries.
What could go wrong: This is a small pilot study with only 57 participants, so results may not apply to all cancer types. The scanner's accuracy needs to be confirmed against standard lab tests, and it may not work for all tumor locations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms oral cavity squamous cell carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEAD AND NECK CANCERS PROSTATE CANCER SURGERY

Contacts and locations

Locations

University Hospitals Coventry and Warwickshire NHS Trust

Coventry, CV2 2DX, United Kingdom

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